منابع مشابه
Drug dosing during continuous renal replacement therapy.
Continuous renal replacement therapy (CRRT) has given clinicians an important option in the care of critically ill patients. The slow and continuous dialysate and ultrafiltrate flow rates that are employed with CRRT can yield drug clearances similar to an analogous glomerular filtration rate of the native kidneys. Advantages such as superior volume control, excellent metabolic control, and hemo...
متن کاملVigabatrin dosing during haemodialysis
The antiepileptic drug vigabatrin has shown efficacy in the treatment of patients with refractory epilepsy. Unlike many other antiepileptics it is not bound to plasma protein and mainly eliminated by the kidney. Although the therapeutic and toxic serum concentration range is not clearly defined and efficacy and toxicity are not closely correlated with the dose, factors decreasing vigabatrin eli...
متن کاملHypothermia during Avalanche Burial
Core body temperature cooling during avalanche burial results in hypothermia, and further core temperature cooling during extrication and evacuation of an avalanche burial victim may result in more severe hypothermia. We performed two studies measuring the rate of core body temperature cooling during snow burial and after extrication from snow burial. Subjects were completely buried in a large ...
متن کاملAssessment of kidney function for drug dosing.
The effort to improve the identification and management of patients with chronic kidney disease (CKD) is based on implementing more precise means of assessing kidney function and kidney damage in the clinical setting. Over the past decade, the clinical chemistry community has adopted routine reporting of estimated GFR (eGFR) calculated from the Modification of Diet in Renal Disease (MDRD) Study...
متن کاملLight-triggered molecule-scale drug dosing devices.
The ability to control drug dosing in terms of quantity, location, and time is a key goal for drug delivery science,1 as improved control maximizes therapeutic effect while minimizing side effects.2 Systems responsive to a stimulus such as temperature,3 pH,4 applied magnetic5 or electrical6 field, ultrasound,7 light,8 or enzymatic action9 have been proposed as triggered delivery systems. Howeve...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatric Critical Care Medicine
سال: 2013
ISSN: 1529-7535
DOI: 10.1097/pcc.0b013e31826775cd